时 间：2018年5月21日（周一）10:00

地 点：588888纽约国际官方网站樱顶老图书馆

主讲人：David W. Christianson 美国宾夕法尼亚州立大学教授

题 目：Structural Biology and Chemistry of Histone Deacetylases in Human Disease and Drug Discovery

主讲人简介：

David W. Christianson教授于哈佛大学先后获得了学士、硕士以及博士学位，并在随后的28年时间内在宾夕法尼亚大学化学系开展学术研究。David W. Christianson教授长期致力于金属依赖性脱乙酰酶，精氨酸酶和萜类生物合成酶等酶的结构与功能的研究。迄今为止，已成功在Science，Nature，Nature Structural & Molecular Biology，JACS，PNAS，Nature Communication等多个国际顶级期刊上发表一系列重要的科学论文。

他的成就使其获得了众多奖项，包括美国化学学会颁发的辉瑞酶学化学奖和生物学过程化学Repligen奖，哈佛大学拉德克利夫高级研究学院的Elizabeth S.和Richard M. Cashin研究员以及哈佛大学化学与化学生物学客座教授。

Brief Introduction of Professor David W. Christianson

Professor David W. Christianson received the AB, AM, and PhD from Harvard University before moving to the University of Pennsylvania, where he has been a member of the faculty for 28 years. His current research focuses on structural and function of metal-dependent arginases, deacetylases, and enzymes of terpenoid biosynthesis. At present, he had published series of papers in top professional journals suchas Science,Nature, Nature Structural & Molecular Biology, JACS, PNAS, Nature Communication.

His accomplishments have been recognized by numerous awards, including the Pfizer Award in Enzyme Chemistry and the Repligen Award in Chemistry of Biological Processes from the American Chemical Society, and Fellowships from the John Simon Guggenheim Memorial Foundation, the Radcliffe Institute for Advanced Study at Harvard University, and the visiting Professor of Chemistry and Chemical Biology of Harvard University